Ginsenoside Re Mitigates 6-Hydroxydopamine-Induced Oxidative Stress through Upregulation of GPX4
نویسندگان
چکیده
منابع مشابه
Effects of Ferulago angulata Extract Against Oxidative Stress Induced by 6-hydroxydopamine in Rats
Background: Parkinson's disease is one of the prevalent degenerative diseases of the neural system. Oxidative stress, which has been recognized as the most important factor of Parkinson's disease, plays a main role in the death of neurons in this disease. Antioxidants have a proved role in the prevention of oxidative stress. Objective: Considering the presence of evidence regarding antioxid...
متن کاملDefensive Properties of Ginsenoside Re against UV-B-Induced Oxidative Stress through Up-Regulating Glutathione and Superoxide Dismutase in HaCaT Keratinocytes
Ginseng is now used worldwide as a traditional Oriental medicine. Ginsenosides, alsoknown as ginseng saponins, are responsible for most pharmacological efficacies of ginseng.This work aimed to assess the novel skin anti-photoaging potential of ginsenoside Re (Re), aprotopanaxatriol-type ginsenoside, by analyzing reactive oxygen species (ROS), pro-matrixmetalloproteinase-2 (proMMP-2) and -9 (pro...
متن کاملDefensive Properties of Ginsenoside Re against UV-B-Induced Oxidative Stress through Up-Regulating Glutathione and Superoxide Dismutase in HaCaT Keratinocytes
Ginseng is now used worldwide as a traditional Oriental medicine. Ginsenosides, alsoknown as ginseng saponins, are responsible for most pharmacological efficacies of ginseng.This work aimed to assess the novel skin anti-photoaging potential of ginsenoside Re (Re), aprotopanaxatriol-type ginsenoside, by analyzing reactive oxygen species (ROS), pro-matrixmetalloproteinase-2 (proMMP-2) and -9 (pro...
متن کاملMangiferin ameliorates 6-hydroxydopamine-induced cytotoxicity and oxidative stress in ketamine model of schizophrenia.
BACKGROUND Accumulating evidence indicates that mangiferin (MGF), a natural xanthone, by virtue of its antioxidant and antiinflammatory properties is neuroprotective. Here we sought to verify the cytoprotective role of MGF on cultured rat primary mesencephalic cells exposed to 6-hydroxydopamine (6-OHDA) in vitro, and the MGFs anti-inflammatory potential in mouse model of ketamine-induced schizo...
متن کاملeffects of ferulago angulata extract against oxidative stress induced by 6-hydroxydopamine in rats
background: parkinson's disease is one of the prevalent degenerative diseases of the neural system. oxidative stress, which has been recognized as the most important factor of parkinson's disease, plays a main role in the death of neurons in this disease. antioxidants have a proved role in the prevention of oxidative stress. objective: considering the presence of evidence regarding antioxidant ...
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ژورنال
عنوان ژورنال: Molecules
سال: 2020
ISSN: 1420-3049
DOI: 10.3390/molecules25010188